College Football Top 25 Week 10 Predictions, Betting Odds & TV Schedule

Updated Nov. 4, 2023 8:36 p.m. ET

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The No. 14 Missouri Tigers and the No. 1 Georgia Bulldogs take the field for one of 20 games on the college football slate in Week 10 that include a ranked team.

For a breakdown of all the big games in college football this week, check out our betting preview below.

Week 10 Betting Lines & Game Info

No. 19 Tennessee Volunteers vs. UConn Huskies

Odds & Prediction

• Spread: Volunteers (-35)
• Moneyline: Volunteers , Huskies
• Total: 55 points
• Prediction: Tennessee 40, UConn 11

How to Watch

• Game Date: Saturday, November 4
• Game Time: 12:00 PM ET
• TV Channel: SEC Network
• Location: Knoxville, Tennessee

No. 11 Ole Miss Rebels vs. Texas A&M Aggies

Odds & Prediction

• Spread: Rebels (-3)
• Moneyline: Rebels -148, Aggies +124
• Total: 52 points
• Prediction: Ole Miss 33, Texas A&M 22

How to Watch

• Game Date: Saturday, November 4
• Game Time: 12:00 PM ET
• TV Channel: ESPN
• Location: Oxford, Mississippi

No. 7 Texas Longhorns vs. No. 25 Kansas State Wildcats

Odds & Prediction

• Spread: Longhorns (-3.5)
• Moneyline: Longhorns -180, Wildcats +150
• Total: 50 points
• Prediction: Texas 27, Kansas State 26

How to Watch

• Game Date: Saturday, November 4
• Game Time: 12:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Austin, Texas

Clemson Tigers vs. No. 12 Notre Dame Fighting Irish

Odds & Prediction

• Spread: Fighting Irish (-3.5)
• Moneyline: Fighting Irish -170, Tigers +142
• Total: 43 points
• Prediction: Notre Dame 30, Clemson 19

How to Watch

• Game Date: Saturday, November 4
• Game Time: 12:00 PM ET
• TV Channel: ABC
• Location: Berkeley, California

No. 18 Utah Utes vs. Arizona State Sun Devils

Odds & Prediction

• Spread: Utes (-10)
• Moneyline: Utes -375, Sun Devils +295
• Total: 39 points
• Prediction: Utah 29, Arizona State 14

How to Watch

• Game Date: Saturday, November 4
• Game Time: 2:00 PM ET
• TV Channel: Pac-12 Network
• Location: Salt Lake City, Utah

No. 17 Air Force Falcons vs. Army Black Knights

Odds & Prediction

• Spread: Falcons (-17.5)
• Moneyline: Falcons -1000, Black Knights +650
• Total: 32 points
• Prediction: Air Force 37, Army 8

How to Watch

• Game Date: Saturday, November 4
• Game Time: 2:30 PM ET
• TV Channel: CBS Sports Network
• Location: Denver, Colorado

Pittsburgh Panthers vs. No. 4 Florida State Seminoles

Odds & Prediction

• Spread: Seminoles (-21)
• Moneyline: Seminoles -1350, Panthers +800
• Total: 49 points
• Prediction: Florida State 41, Pittsburgh 14

How to Watch

• Game Date: Saturday, November 4
• Game Time: 3:30 PM ET
• TV Channel: ESPN
• Location: Pittsburgh, Pennsylvania

Oklahoma State Cowboys vs. No. 10 Oklahoma Sooners

Odds & Prediction

• Spread: Sooners (-5.5)
• Moneyline: Sooners -225, Cowboys +185
• Total: 62 points
• Prediction: Oklahoma 32, Oklahoma State 27

How to Watch

• Game Date: Saturday, November 4
• Game Time: 3:30 PM ET
• TV Channel: ABC
• Location: Stillwater, Oklahoma

East Carolina Pirates vs. No. 21 Tulane Green Wave

Odds & Prediction

• Spread: Green Wave (-17)
• Moneyline: Green Wave -850, Pirates +575
• Total: 44.5 points
• Prediction: Tulane 34, East Carolina 15

How to Watch

• Game Date: Saturday, November 4
• Game Time: 3:30 PM ET
• TV Channel: ESPNU
• Location: Greenville, North Carolina

No. 15 Louisville Cardinals vs. Virginia Tech Hokies

Odds & Prediction

• Spread: Cardinals (-8.5)
• Moneyline: Cardinals -340, Hokies +270
• Total: 47 points
• Prediction: Louisville 32, Virginia Tech 18

How to Watch

• Game Date: Saturday, November 4
• Game Time: 3:30 PM ET
• TV Channel: ACC Network
• Location: Louisville, Kentucky

Georgia State Panthers vs. No. 23 James Madison Dukes

Odds & Prediction

• Spread: Dukes (-6)
• Moneyline: Dukes -238, Panthers +195
• Total: 52 points
• Prediction: James Madison 30, Georgia State 23

How to Watch

• Game Date: Saturday, November 4
• Game Time: 3:30 PM ET
• TV Channel: ESPN2
• Location: Atlanta, Georgia

No. 1 Georgia Bulldogs vs. No. 14 Missouri Tigers

Odds & Prediction

• Spread: Bulldogs (-15)
• Moneyline: Bulldogs -700, Tigers +500
• Total: 55.5 points
• Prediction: Georgia 31, Missouri 26

How to Watch

• Game Date: Saturday, November 4
• Game Time: 3:30 PM ET
• TV Channel: CBS
• Location: Athens, Georgia

Maryland Terrapins vs. No. 9 Penn State Nittany Lions

Odds & Prediction

• Spread: Nittany Lions (-7.5)
• Moneyline: Nittany Lions -290, Terrapins +235
• Total: 49.5 points
• Prediction: Penn State 31, Maryland 20

How to Watch

• Game Date: Saturday, November 4
• Game Time: 3:30 PM ET
• TV Channel: Watch Online: FOX
• Location: College Park, Maryland

No. 6 Oregon Ducks vs. California Golden Bears

Odds & Prediction

• Spread: Ducks (-26.5)
• Moneyline: Ducks -4000, Golden Bears +1600
• Total: 61 points
• Prediction: Oregon 44, Cal 19

How to Watch

• Game Date: Saturday, November 4
• Game Time: 5:30 PM ET
• TV Channel: Pac-12 Network
• Location: Eugene, Oregon

Iowa State Cyclones vs. No. 22 Kansas Jayhawks

Odds & Prediction

• Spread: Cyclones (-3)
• Moneyline: Cyclones -148, Jayhawks +124
• Total: 53.5 points
• Prediction: Kansas 28, Iowa State 27

How to Watch

• Game Date: Saturday, November 4
• Game Time: 7:00 PM ET
• TV Channel: ESPN
• Location: Ames, Iowa

No. 2 Michigan Wolverines vs. Purdue Boilermakers

Odds & Prediction

• Spread: Wolverines (-32)
• Moneyline: Wolverines -9000, Boilermakers +2500
• Total: 54 points
• Prediction: Michigan 41, Purdue 8

How to Watch

• Game Date: Saturday, November 4
• Game Time: 7:30 PM ET
• TV Channel: NBC
• Location: Ann Arbor, Michigan

No. 24 USC Trojans vs. No. 5 Washington Huskies

Odds & Prediction

• Spread: Huskies (-2.5)
• Moneyline: Huskies -142, Trojans +120
• Total: 76 points
• Prediction: Washington 37, USC 33

How to Watch

• Game Date: Saturday, November 4
• Game Time: 7:30 PM ET
• TV Channel: ABC
• Location: Los Angeles, California

No. 8 Alabama Crimson Tide vs. No. 13 LSU Tigers

Odds & Prediction

• Spread: Crimson Tide (-3)
• Moneyline: Crimson Tide -166, Tigers +140
• Total: 61.5 points
• Prediction: Alabama 31, LSU 29

How to Watch

• Game Date: Saturday, November 4
• Game Time: 7:45 PM ET
• TV Channel: CBS
• Location: Tuscaloosa, Alabama

Colorado Buffaloes vs. No. 16 Oregon State Beavers

Odds & Prediction

• Spread: Beavers (-13)
• Moneyline: Beavers -535, Buffaloes +400
• Total: 59 points
• Prediction: Oregon State 35, Colorado 27

How to Watch

• Game Date: Saturday, November 4
• Game Time: 10:00 PM ET
• TV Channel: ESPN
• Location: Boulder, Colorado

Arizona Wildcats vs. No. 20 UCLA Bruins

Odds & Prediction

• Spread: Bruins (-2.5)
• Moneyline: Bruins -135, Wildcats +114
• Total: 49.5 points
• Prediction: Arizona 26, UCLA 22

How to Watch

• Game Date: Saturday, November 4
• Game Time: 10:30 PM ET
• TV Channel: Watch Online: Fox Sports 1
• Location: Tucson, Arizona

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