With the Tennessee Titans ranked 27th against the pass, allowing over 273 pass yards per game, Jake Locker returning from injury, and Ryan Tannehill without an interception since September 30th (a span of 107 passes - think about that for a second), the stars seemed to align for a bye-week rental start for the rookie quarterback.  Instead, Tannehill had his worst game since his NFL debut back in Week 1.  He finished 23-39 for 217 yards with three interceptions.  The 2.6 fantasy points (standard scoring) aren't going to earn many fantasy owners a "W" this week.  He now has five touchdowns and nine interceptions on the season with Buffalo (another temptation) on tap next week. - Ryan Fowler

Smith was one of my suggested "Sits" this week.  Going up against Denver's Champ Bailey was not a favorable matchup for the Panthers' top receiver.  Turned out Cam Newton's favorite target was tight end Greg Olsen (102 yards, two TDs) and not Smith who finished with one reception for 19 yards on seven targets. - Ryan Fowler

WATCH: Week 10 Fantasy Recap

Reggie Bush got benched in Week 10.  Yeah, it was that bad.  However, the running back admitted after the game "If I'm a coach, I would have benched myself too."  Not sure if that makes fantasy owners feel any better as Bush has now gone five games where he's failed to rush for 60 or more yards.  His two games with over 100 total yards came in Weeks 1 and 2.  His final Week 10 stat line was four carries for 21 yards with one reception for eight yards and a fumble (the reason for the pine riding).  Still, he's a must-start in Week 11 vs. Buffalo. - Ryan Fowler (Twitter: @FOXSportsFowler)

WATCH: Week 10 Fantasy Recap

Truth be told, I sold high on Mikel Leshoure this past week and traded him in a package deal.  Leshoure's three-touchdown performance last week, though promising, was far from what owners should come to expect from the running back on a weekly basis - at least in his first season.  The Lions' offensive script against Minnesota was very similar to previous games as Matthew Stafford and company didn't do much in the first half before erupting in the fourth quarter.  Calvin Johnson (honorary fantasy "Stud" with over 200 receiving yards) became the focal point as the rushing game was an afterthought.  Detroit only ran the ball 17 times total.  Leshoure finished with 43 yards with a five-yard catch and no trips to the end zone. - Ryan Fowler

To really drive home how bad Eli Manning was in Week 10, Blaine Gabbert (7.4) scored more fantasy points than the Giants quaterback (2.7).  Manning has racked up 11.7 fantasy points COMBINED the last three games.  He's 54-99 with no touchdowns and four interceptions during that stretch.  However, and this is important, you want Manning on your team the rest of the season.  Over the next three weeks, Manning faces Green Bay's banged up secondary (no Woodson), Washington's soft pass defense and New Orleans swiss-cheese defense.  All signs point to Manning turning this around with Victor Cruz and Hakeem Nicks on the field.  Ahmad Bradshaw, David Wilson and Andre Brown do need to improve in order to keep some of the heat off Manning. - Ryan Fowler

WATCH: Week 10 Fantasy Recap

With no apparent signs of a rushing game (21 carries for 52 yards Week 10), Cam Newton is looking Greg Olsen's direction often.  For the second week in a row, the tight end led the Panthers in targets.  He caught nine of the 10 balls thrown his direction for 102 yards with two touchdowns.  The 102 yards are a career high and it's his first 100-yard game in the regular season.  He posted 113 yards in a 2010 (2011) playoff game while with the Chicago Bears (vs. SEA). - Ryan Fowler

The San Diego Chargers brought in Robert Meachem this past offseason to "replace" Vincent Jackson in the starting lineup.  Perhaps they should have looked at Danario Alexander as second deep threat instead.  For the second game in a row, granted against subpar pass defenses, Alexander shined in the Chargers' passing game.  He finished with five receptions for 134 yards with an 80-yard touchdown to round out a superb flier fantasy day.  With Malcom Floyd and Antonio Gates garnering the most attention, Alexander may continue to roam free.  - Ryan Fowler

Tennessee's defense flipped the script in Week 10.  The Titans' defense must have spent the week taking film notes on the Bears.  A week after Chicago's DST embarassed the Titans on their home field, Tennessee traveled to Miami and picked Ryan Tannehill off three times (one a pick-six), sacked him twice, recovered a Reggie Bush fumble, and held Miami's offense to one Dan Carpenter second-quarter field goal.  Add it all up and the Titans provided owners a season-high 23 fantasy points. - Ryan Fowler

Heading into his Week 10 matchup with the Raiders, Joe Flacco averaged just over 180 passing yards over his last four games with three touchdowns and three interceptions.  It's one of those stretches that mutes all that "elite" quarterback chatter in the NFL and fantasy circles.  However, with a tasty matchup against the Raiders on tap, Flacco took full advantage.  He finished 21-33 for 341 yards with three touchdowns, one interception and one rushing touchdown.  As of print time, his 35.7 fantasy points led in the clubhouse. - Ryan Fowler

WATCH: Week 10 Fantasy Recap

During their four-game losing streak, Andy Dalton's seven interceptions watered down the six touchdowns and whispers of a "sophomore slump" were everywhere.  New York's pass defense, though always a question mark with injuries, led the NFL in interceptions heading into Week 10 and presented a tough matchup for the young quarterback.  Dalton answered the call and outperformed two-time Super Bowl champion Eli Manning in the passing game Sunday.  Dalton completed 70 percent of his passes for 199 yards with four touchdowns as he connected with A.J. Green, Jermaine Gresham, Andrew Hawkins and Mohamed Sanu for six.  The 31.8 fantasy points are a season high for the "Red Rifle." - Ryan Fowler (Twitter: @FOXSportsFowler)