by Mike Harmon

With a plethora of injuries affecting fantasy lineups this weekend, fantasy owners will be reaching deep for their second running back or third wide receiver options. The bye week claims several top running backs, wide receivers and the machine-like Kurt Warner. Who steps up to fill the void?

Let's start the review with part one of this week's Lineup Calls .

Top 10 Quarterbacks (not named Peyton Manning, Tony Romo, Philip Rivers, Drew Brees, Brett Favre, Aaron Rodgers and Jay Cutler)

Matt Schaub vs. Detroit

Who doesn't love the quarterback draw? Schaub returned to the lineup and produced a strong effort against the Dolphins including frequent hook-ups with Andre Johnson and a phenomenal late drive that was capped by the QB keeper. He topped 300 yards for the second straight start and showed more poise in the pocket. This is a dream matchup against a Detroit team that's shuffled the deck to get ready for 2009.

Kyle Orton vs. Minnesota

Orton failed to extend his multi-touchdown streak last week against the Falcons, although his touchdown toss to Rashied Davis was mighty impressive. I expect Orton to keep flinging downfield this weekend against the Vikings. Of course, the big factor in this game is whether the Chicago offensive line can stave off Jared Allen and company. If so, he'll make plays against this secondary.

Ben Roethlisberger at Cincinnati

Roethlisberger posted his best game of the year in Week 5 against the banged-up Jacksonville secondary. He returns following the bye week in a second matchup against the Bengals. Granted, the pass defense numbers posted by the Bengals are solid, but they're being run over by seemingly every opponent. Look for Roethlisberger to take advantage of the opportunities afforded by Dick LeBeau's defense against Ryan Fitzpatrick.

Derek Anderson at Washington

Welcome back, Derek Anderson! The Browns' struggling quarterback posted his best game of the season, finally eclipsing the 200-yard mark during Monday's thrashing of the Giants. The offensive line protected him well, allowing Braylon Edwards to work downfield. One thing lacking from Washington is a persistent pass rush, and that's music to the ears of Anderson owners. The looming return of Kellen Winslow obviously gives this unit a boost.

Trent Edwards vs. San Diego

Edwards is set to return to the lineup for a highly-anticipated Week 7 affair against the Chargers. San Diego was able to jump all over the Patriots early last week, thereby allowing the defensive line to pin its ears back and get after Matt Cassel. I don't expect that to occur this weekend. Edwards is efficient and unflappable and has led this unit well. Now, he just needs someone to pick up the blitzing safety.

Brad Johnson at St. Louis

If the Dallas offensive line can do a better job of protecting the quarterback in Week 7 (last week was a joke!), Johnson could post a big day against the Rams. St. Louis has generated just one interception this season against eight touchdowns, surrendering an average of 234 passing yards per game. Johnson knows how to efficiently work an offense. Now, it's just a question of whether he tries to force too many balls to Terrell Owens and Roy Williams.

Jake Delhomme vs. New Orleans

Delhomme posted one of his worst games ever against the Buccaneers in Week 6. He threw three interceptions and could've thrown many more if the Tampa Bay defensive backs could catch. The Carolina offensive line is healthy and should provide him time to settle in the pocket. That portends to a strong rebound effort against an inconsistent New Orleans secondary.

Jeff Garcia looked strong last week and should be able to do the same at home against the Seahawks on Sunday. (Doug Pensinger / Getty Images)

Jeff Garcia vs. Seattle

Garcia isn't flashy, but he's efficient. There's also an outside chance Joey Galloway finally returns from his foot injury. Oh, and the Seattle defense is on the hook for a trip to Tampa. Seattle's allowed 229.6 passing yards and 1.8 passing touchdowns per game. The Tampa Bay defense will make things difficult for Seneca Wallace and provide Garcia with short fields. I don't expect we see much more than 175 yards from Garcia this week, but I'm calling for multiple touchdowns.

Eli Manning vs. San Francisco

Manning took a hard hit in last week's blowout loss to Cleveland, and his status for Week 7 is in a bit of doubt. He had his worst game in recent memory, tossing three interceptions, including the back-breaking errant pass returned for a touchdown. He'll rebound well this weekend against San Francisco, though. His potent running game will traverse the field, and the defense will afford him short fields to work.

Jason Campbell vs. Cleveland

Campbell's gone scoreless in back-to-back games, and last week's loss to the Rams was quite shocking. I'm not expecting a huge rebound performance this weekend against a Cleveland team that seems to have had a psychological breakthrough in the past two weeks. However, I do anticipate we see more involvement from Santana Moss, and Antwaan Randle El's a great sleeper play as he works underneath coverage. I'm calling on Campbell to top 200 yards with one or two scores.

Quarterback Sleeper Candidates

Matt Cassel vs. Denver

Cassel played terribly last week. There's no way to sugarcoat it. The San Diego pass rush gave him happy feet and he repeatedly underthrew his options. With that said, I'm expecting a bounce-back effort in front of the home crowd. The Denver defense has been puzzling, surrendering 255.5 passing yards and 1.5 passing touchdowns per game. Randy Moss owners, rejoice! You're getting a score this week.

Gus Frerotte at Chicago

Frerotte was the super sleeper of Week 6, and he nearly came through with a 300-yard performance. Overall, it was a decent, albeit unspectacular, effort against the Lions. I anticipate another strong performance from him this weekend against a banged-up Chicago defense. Both Charles Tillman and Nathan Vasher may be sidelined for this game. That would afford Frerotte opportunities to connect with former Chicago receiver Bernard Berrian downfield.

Marc Bulger vs. Dallas

The Rams put up 19 points last week, and fantasy owners were quick to see whether Steven Jackson or Bulger accounted for the scores. Imagine their surprise when they saw the box score and Bulger's final stat line. That was last week. I anticipate much better returns in Week 7 against the Dallas secondary provided, of course, that the St. Louis offensive line can keep Bulger upright. I'm most interested in watching Bulger's growing comfort with rookie Donnie Avery, who will eventually become a thrilling deep ball option.

Quarterback Flop Candidates

J.T. O'Sullivan at New York Giants

Simply put, the offensive line in San Francisco undercuts anything O'Sullivan might be able to accomplish. He spends most of his time retreating for his life. He's averaging two turnovers and nearly four sacks per game. The Giants were embarrassed by Cleveland in Week 6. I anticipate a strong rebound effort against the 49ers this week.

Chad Pennington vs. Baltimore

I've been leading the Pennington bandwagon this season, citing his efficiency on radio stations nationwide and in my "Fantasy Decision '08" videos. However, this is a difficult proposition against a Baltimore defense that was embarrassed last weekend. To quote The Who (as it seems everyone does these days), "We won't get fooled again." Look for Ray Lewis, Ed Reed and company to come strong against Pennington this week. Even with injuries in the secondary, I don't know that the Dolphins handle the front seven.

Top 10 Running Backs (not named LaDainian Tomlinson, Adrian Peterson, Marion Barber, Steven Jackson, Clinton Portis, Frank Gore or Brian Westbrook)

Chris Johnson at Kansas City

Johnson stands as the Play of the Week. The Kansas City run defense surrenders 182.2 rushing yards per game. Is that enough? Johnson's assumed the lead role in this dual backfield, with LenDale White still somewhat affected by a shoulder injury. Johnson's averaging 90 total yards per game and earns a "must start" tag this week.

Ryan Grant vs. Indianapolis

Yes, I'm not giving up on Grant entirely just yet. He rushed for 83 yards last week, a solid effort until you note he needed 33 attempts to reach that level. He won't need that many carries to top that mark against the Colts, particularly with Aaron Rodgers still flinging the ball downfield (can anyone stop Greg Jennings?).

Steve Slaton vs. Detroit

Slaton finds his way onto the list once again. Of course, just look at the abbreviation of the opponent. Granted, the Lions did a good job containing Adrian Peterson last week, forcing Gus Frerotte to work downfield. With Matt Schaub under center, it doesn't work the same way. Schaub will open up the playbook and take shots downfield, thereby opening running lanes for Slaton. His ability to catch the ball out of the backfield is most enticing here.

With Joseph Addai's latest injury, Dominic Rhodes suddenly becomes a solid play this week. (Andy Lyons / Getty Images)

Dominic Rhodes at Green Bay

Rhodes returns to the fantasy radar given the injuries to Joseph Addai (2-4 weeks) and Mike Hart (IR). He assumed a heavy workload last week, as the Colts sat on the ball after jumping all over the injury-depleted Baltimore secondary. Rhodes will again rise toward 20 touches this week given the Packers' struggles against the run. Green Bay allows 153 rushing yards per game.

Thomas Jones at Oakland

Jones was running out of chances with fantasy owners, but he stood and delivered with his back to the wall against Cincinnati. He scored three touchdowns (two rushing), giving him one more touchdown last week than Jones earned in all of 2007! The Raiders are surrendering 115 rushing yards and 1.6 rushing touchdowns per game. With the Oakland offense sputtering, I'm banking on another big day for Brett Favre and this offense.

Jamal Lewis at Washington

A big pass play to Braylon Edwards allowed Lewis to pick up a touchdown for gambling fantasy owners who eschewed other seemingly better options. The Browns' early lead allowed Lewis to shoulder a heavy load and rack up 88 rushing yards, his best effort of the year. The Redskins are allowing only 83.8 rushing yards per game, but the return of Kellen Winslow (expected as of this writing) and the renewed confidence of Derek Anderson has me optimistic that Lewis scores for the third straight week.

Reggie Bush at Carolina

Bush has been slowed somewhat by a knee injury early in the practice week, but he told reporters he's anticipating playing this week. He's averaged 100 total yards per game while racking up 41 receptions. The Panthers are a solid defensive unit, regardless of what you saw last week against the Buccaneers. Bush is averaging just 39.8 rushing yards per game, but the appeal here is the rushing/receiving combination.

Warrick Dunn vs. Seattle

Don't call it a comeback! Dunn's receiving ample opportunities from Jon Gruden on the ground, and he rumbled for 115 yards last week in the romp over Carolina. He's averaging 12 carries per game, and this is positively a great spot for he and tag-team partner Earnest Graham to run wild. The Seattle defense is allowing 126 rushing yards and one rushing touchdown per game. Look for Dunn to top 80 rushing yards while adding several receptions.

Marshawn Lynch vs. San Diego

Lynch has yet to crack 100 rushing yards in a game this season. However, fantasy owners can't be too depressed about his four touchdowns to start the year. I expect the Bills to come out running against the Chargers following the bye week. Trent Edwards will be back under center to direct traffic, and I expect this unit to perform well. San Diego's allowing 112.2 rushing yards and 0.5 rushing touchdowns per game. I'm also intrigued that Lynch has caught three or more passes in four of the Bills' first five games.

Michael Pittman at New England

Pittman rushed for 109 yards last week as the sole option out of the Denver backfield. Sure, the Broncos lost and Mike Shanahan might turn back to throwing early and often (especially after watching Philip Rivers go nuts in Week 6), but Pittman represents a solid option for fantasy owners this week. The Patriots are allowing 119.4 rushing yards per game, and fantasy owners can bank on him seeing any goal-line rushing efforts.

Running Back Sleeper Candidates

Mewelde Moore at Cincinnati

Willie Parker missed Wednesday's practice because of a flare-up of his knee injury, thereby thrusting Moore back onto the fantasy radar. Moore rushed for 99 yards in his lone start for the Steelers, and he could run wild like Hulkamania in the '80s if given a chance this weekend. The Cincinnati run defense is allowing 156.8 yards and 1.3 rushing touchdowns per game.

Sammy Morris vs. Denver

Morris scored last week against the Chargers, although his 2.6-yard per carry average isn't awe-inspiring. He's a solid longshot bet this weekend against the Denver run defense. The Broncos allow 137.5 rushing yards per game. Naturally, the Patriots play a chess game with fantasy owners (shades of Denver, anyone?) given the number of backs on the roster. However, Morris is the top option out of this crew on a weekly basis.

Tashard Choice at St. Louis

Choice, a fourth-round pick out of Georgia Tech, leaps onto the fantasy radar in the wake of Felix Jones' injury. He becomes the No. 2 pick behind Marion Barber, and I believe Choice sees a significant workload against the Rams. St. Louis has surrendered 169 rushing yards per game, and I expect the Cowboys to force the issue on the ground. Brad Johnson works efficiently under center and will take a few shots downfield. However, the run game will be front and center.

Running Back Flop Candidates

Julius Jones at Tampa Bay

The Seahawks have no choice but to lean on Jones heavily. Matt Hasselbeck will sit again this week, and quarterback turned receiver turned quarterback again, Seneca Wallace, will start this game. As such, I'm not expecting much help out of the passing game. Jones has averaged just 3.62 rushing yards per attempt in his past two games, and this is a difficult spot against a Tampa Bay run defense that's yet to allow a rushing touchdown in 2008.

Oakland Running Backs vs. New York Jets

Everyone's been fired up about the stellar play (well, mostly) of Brett Favre in New York and the explosiveness of the offense. However, Eric Mangini's defense is starting to gel and become a formidable unit itself. Opposing running backs average a paltry 69 yards per game against the New York front. Now, it's possible McFadden or Fargas busts a long one, but don't count on support from the passing game. I'll stay away from this three-headed monster in Week 7.

Ronnie Brown vs. Baltimore

Brown's return to the upper-class of running backs is one of the year's great stories. However, this is a tough, tough spot. Dominic Rhodes rushed for 73 yards and a score last weekend for the Colts, becoming the first running back to score against the Ravens. Baltimore allows 66.4 rushing yards per game, making this a difficult proposition. You have to start him given the state of the running back position across the league, but temper those expectations.

Larry Johnson vs. Tennessee

The assault charge leveled against Johnson will force him out of Week 7 against the Titans. I was already calling for owners to sit him down, but now the point is moot. Look elsewhere.

Top 10 Wide Receivers (exclude Larry Fitzgerald, Anquan Boldin, Brandon Marshall, Randy Moss, Plaxico Burress, Wes Welker, T.J. Houshmandzadeh, Andre Johnson, Marques Colston, Greg Jennings, Steve Smith and Terrell Owens)

Bernard Berrian can't wait to face off against his old team this weekend. (Chris Graythen / Getty Images)

Bernard Berrian at Chicago

Berrian finally got healthy, and he's paid big dividends for the Minnesota offense. He's caught 16 passes in the past three weeks and has scored in back-to-back games. He certainly wants to perform well against his former squad. The Chicago secondary's been impacted by injuries, and I suspect Berrian could find success on the deep ball.

Marvin Harrison at Green Bay

Harrison had his breakthrough game last week, catching an early 67-yard touchdown from Peyton Manning to begin the rout against the Ravens. I won't say the Colts are "back," but I'm certainly encouraged by what I've seen from Manning the past two weeks. This week's matchup is intriguing on a number of levels, and I expect the Colts to start quickly once again. Harrison will make his mark against this secondary.

Calvin Johnson at Houston

The deal that sent Roy Williams to the Cowboys leaves Johnson as the last man standing in Detroit. He's undoubtedly set to see routine double-teams, and the return of Dunta Robinson to action certainly bolsters the Houston secondary. I have absolutely no idea what to expect from Dan Orlovsky, but he has no choice to force the ball into Johnson repeatedly.

Hines Ward at Cincinnati

The Steelers return to action following the bye, and Ward still doesn't have an answer as to why the NFL lifted $5K out of his pocket. Frankly, we're all still a tad curious. In any event, Ward has his best game of the season in Week 5 against the Jaguars, hauling in seven catches for 90 yards and his second touchdown of the year. I know it doesn't carry year-to-year, but a quick glance at his efforts against Cincinnati last year makes you salivate. In two games, he caught 19 passes for 178 yards and four touchdowns. Light it up. The Steelers will take advantage of the opportunities generated by the defense.

Jerricho Cotchery at Oakland

Cotchery's caught 22 passes during the Jets' past three games. Fantasy owners may be frustrated by the inconsistent end zone trips from him this season, but we shouldn't discount the near-miss last week (he caught a touchdown pass that was negated by a penalty). Barring some unforeseen circumstances, the Jets should steamroll the Raiders much in the same way that the Saints did last week.

Lee Evans vs. San Diego

Don't look now, but "Mr. December" made an early appearance in 2008. Evans has scored in back-to-back games and has caught two or more passes in each game. More importantly, he hasn't finished a game with fewer than 65 receiving yards. Trent Edwards is expected back under center, and that bodes well for the offense against the San Diego pass defense. I don't expect this unit to crumble as the New England offense did in Week 6.

Kevin Walter vs. Detroit

Walter caught a great pass from Matt Schaub late in the comeback win over Miami last week, finishing the game with four receptions for 98 yards. He and the Texans have an attractive matchup on the schedule this week against the imploding Lions defense. Detroit allowed 250 passing yards and nearly two passing touchdowns per game. Schaub could eclipse 300 yards for the third straight start. Walter will get his fair share of the spoils.

Wes Welker vs. Denver

Matt Cassel may have exhibited happy feet against the Chargers, but he was still able to complete frequent short passes to Welker. He's caught six or more passes in each of the Patriots' first five games, averaging 64.8 yards per game in the process. The Denver defense has been baffling this season. Despite the aptitude of their cornerbacks, the Broncos have been struggling to hold down opposing offenses. I expect those struggles to continue on the road against the Patriots.

Torry Holt vs. Dallas

Holt produced a smallish stat line in the upset win over Washington, generating just 23 receiving yards on five catches. I'm expecting a much more robust contribution this weekend against the Cowboys, whose secondary's been depleted by injuries and the suspension of Adam "Pacman" Jones. Take the veteran Holt against the rookie corners who will try to contain him.

Vincent Jackson at Buffalo

Jackson established a new career mark with 134 receiving yards against the Patriots in Week 6. Rivers exploited the matchup against smaller cornerbacks and worked over the top. I don't expect things to go quite so easily this weekend, but Rivers is clearly comfortable tossing the ball to Jackson downfield. He's caught at least two passes in each game and has not yet finished a game with fewer than 47 receiving yards.

Wide Receiver Sleeper Candidates

Devin Hester vs. Minnesota

Hester's ascent to a consistent receiving option for Kyle Orton came much quicker than anticipated. He scored in back-to-back games, then set new personal bests with six receptions for 87 yards in Week 6 against Atlanta. Assuming the Chicago offensive line can keep Jared Allen and company at bay, Orton should succeed downfield.

Antwaan Randle El vs. Cleveland

Randle El's quietly been a consistent target for Jason Campbell this season. He's averaged 4.3 receptions and 51 receiving yards per game. I'm looking directly to Steve Smith's (NYG) efforts last weekend as a sketch of what we may see from Randle El. Smith settled into the Cleveland zone, amassing 94 receiving yards on nine receptions. The Cleveland defense will work to take Santana Moss away downfield, leaving Randle El to work underneath.

Donnie Avery vs. Dallas

Avery's a deep ball threat whose role in the St. Louis offense is growing each week. He made a huge catch late in the shocking upset win over the Redskins and has caught three or more passes in three straight games. He reached a new career mark last week with 73 receiving yards. The losses of Pacman Jones and Terence Newman leave Avery matched up against a rookie cornerback. I'll take the receiver in that one.

Bobby Wade at Chicago

Wade's quietly become a consistent performer in the Minnesota offense, taking the short routes while Bernard Berrian (another former Bear) wreaks havoc downfield. Wade's averaged five receptions and 57.4 yards per game during the past five weeks. The Chicago secondary's banged up, with both Charles Tillman and Nathan Vasher limited in early-week practices. He's a nice target underneath for Gus Frerotte and warrants a look-see in PPR leagues.

Wide Receiver Flop Candidates

Dwayne Bowe vs. Tennessee

Bowe's the most-targeted receiver on a per game basis. As such, he needs to stay in your lineup. However, don't expect much more than WR3 numbers this weekend against a tough, tough Tennessee defense. The trend's been for teams to come out with suspect efforts out of the bye. I don't believe Jeff Fisher's squad lets down for a moment. The Titans allow only 172 passing yards per game and surrendered only one touchdown through the first five weeks. I expect to see a persistent pass rush once again, and the Tony Gonzalez situation isn't good for anybody.

Chad Ocho Cinco vs. Pittsburgh

Ocho Cinco's yet to top 60 receiving yards in a game and has only scored one touchdown. The Steelers are healthier coming out of the bye week, and Johnson will once again be receiving looks from Ryan Fitzpatrick. This is a tough spot. You keep hoping for the best and don't want to miss his breakout performance. I just don't see it happening against Dick LeBeau's defense, which should terrorize Fitzpatrick.

Isaac Bruce at New York Giants

As expected, Bruce was contained by the Philadelphia defense, which is becoming quite spectacular in keeping opponents' top receivers down. He caught only two passes for 28 yards in that contest, thereby ending his three-game scoring streak. I'm not banking that the 49ers get the offense restarted this weekend against a New York defense eager to reclaim its place at the top of the heap following a miserable Week 6 performance.

Keep your browser locked onto FOXSports.com for all of the latest player and team news as the countdown to kickoff winds down. You can contact me during the "FOX Fantasy Freaks" on FOX Sports Radio on Sunday morning from 10am ET-12pm ET (7am PT-9am PT).

Good luck!