Wenger desperate to keep Van Persie
The Gunners may have already moved to bring in fresh faces Olivier Giroud and Lukas Podolski, but there is still work to be done to convince Van Persie to extend his contract past next summer.
Italian champions Juventus have made their interest clear, while Premier League winners Manchester City are said to be ready to put down a £20million offer with more than £200,000-per-week wages for the Holland striker, who is now away on holiday following a disappointing Euro 2012.
Wenger, though, knows just how important van Persie, 28, is to the club, having netted 37 goals in all competitions as the Gunners eventually secured third place.
Writing in his blog for Eurosport, Wenger said: "We want to keep Robin van Persie at all costs, because we depend on him offensively.
"I have always supported him even in the hardest times, and I hope he will end his career at Arsenal."
Giroud scored 21 goals in 36 league appearances as Montpellier claimed their first Ligue 1 title last season, and will now aim to make an instant impact in England as the Gunners look to deliver a first trophy since 2005.
Wenger is in no doubt the 25-year-old, signed for a reported £13million deal, will fit right in at Emirates Stadium.
"I have known Olivier Giroud for some time," the Frenchman added.
"The first time I saw him, I found he had something intelligent and dangerous. I always said he could score goals and assist his partners.
"Our game is based on cooperation between the players in the offensive phase and he will integrate easily.
"I don't like simple goalscorers, they must also add to the collective.
"He is good in the air which is rare. He is quite complete and has a great room for improvement."
Wenger has been working as a media pundit at the European Championship, and following the departure of Laurent Blanc after France's quarter-final exit, had been linked with taking on a coaching role with the national team.
However, Wenger, 62, remains focused on delivering more success with the Gunners.
Speaking to TV station Telefoot, Wenger said: "There are a lot of names [linked with the France job], but me, I will be very busy with Arsenal where my contract still runs for two years."
The Gunners are now likely to move to offload some of their fringe players - especially in attack, where Morocco international Marouane Chamakh, Mexico forward Carlos Vela and Denmark striker Nicklas Bendtner could all depart.
Costa Rica forward Joel Campbell looks set for another loan spell, this time at Spanish side Real Betis.
"I am going to the world's best league, and I want to play. I want to show what I am capable of."