| Lunes, 12 de Mayo |
| Hora (Este) | Visitante | Local | Lanzador
Visitante | Lanzador
Local | Estadio |
| 12:35 p.m. | Braves | Pirates | Atl: Jair Jurrjens | Pit: Phil Dumatrait | PNC Park
Pittsburgh, Pennsylvania |
| 4:05 p.m. | Blue Jays | Indians | Tor: A.J. Burnett | Cle: Fausto Carmona | Progressive Field
Cleveland, Ohio |
| 4:05 p.m. | Braves | Pirates | Atl: Tim Hudson | Pit: John Van Benschoten | PNC Park
Pittsburgh, Pennsylvania |
| 7:05 p.m. | Red Sox | Twins | Bos: Clay Buchholz | Min: Livan Hernandez | Hubert H. Humphrey Metrodome
Minneapolis, Minnesota |
| 7:10 p.m. | Marlins | Reds | Fla: Burke Badenhop | Cin: Aaron Harang | Great American Ball Park
Cincinnati, Ohio |
| 7:10 p.m. | Nationals | Mets | Was: Odalis Perez | NYM: Nelson Figueroa | Shea Stadium
Flushing, New York |
| 7:10 p.m. | Yankees | Rays | NYY: Chien-Ming Wang | TB: Matt Garza | Tropicana Field
St. Petersburg, Florida |
| 7:35 p.m. | Blue Jays | Indians | Tor: Shaun Marcum | Cle: Cliff Lee | Progressive Field
Cleveland, Ohio |
| 8:05 p.m. | Cardinals | Brewers | StL: Adam Wainwright | Mil: Dave Bush | Miller Park
Milwaukee, Wisconsin |
| 8:05 p.m. | Mariners | Rangers | Sea: Erik Bedard | Tex: Vicente Padilla | Rangers Ballpark in Arlington
Arlington, Texas |
| 8:05 p.m. | Padres | Cubs | SD: Randy Wolf | ChC: Carlos Zambrano | Wrigley Field
Chicago, Illinois |
| 10:05 p.m. | White Sox | Angels | CWS: Mark Buehrle | LAA: Nick Adenhart | Angel Stadium of Anaheim
Anaheim, California |
| 10:15 p.m. | Astros | Giants | Hou: Roy Oswalt | SF: Barry Zito | AT&T Park
San Francisco, California |
| Martes, 13 de Mayo |
| Hora (Este) | Visitante | Local | Lanzador
Visitante | Lanzador
Local | Estadio |
| 7:05 p.m. | Red Sox | Orioles | Bos: Josh Beckett | Bal: Jeremy Guthrie | Oriole Park at Camden Yards
Baltimore, Maryland |
| 7:05 p.m. | Athletics | Indians | Oak: Justin Duchscherer | Cle: Paul Byrd | Progressive Field
Cleveland, Ohio |
| 7:05 p.m. | Braves | Phillies | Atl: Jo-Jo Reyes | Phi: Kyle Kendrick | Citizens Bank Park
Philadelphia, Pennsylvania |
| 7:10 p.m. | Marlins | Reds | Fla: Mark Hendrickson | Cin: Edinson Volquez | Great American Ball Park
Cincinnati, Ohio |
| 7:10 p.m. | Nationals | Mets | Was: John Lannan | NYM: John Maine | Shea Stadium
Flushing, New York |
| 7:10 p.m. | Yankees | Rays | NYY: Mike Mussina | TB: Edwin Jackson | Tropicana Field
St. Petersburg, Florida |
| 8:05 p.m. | Dodgers | Brewers | LAD: Brad Penny | Mil: Carlos Villanueva | Miller Park
Milwaukee, Wisconsin |
| 8:05 p.m. | Mariners | Rangers | Sea: Felix Hernandez | Tex: Kason Gabbard | Rangers Ballpark in Arlington
Arlington, Texas |
| 8:05 p.m. | Padres | Cubs | SD: Shawn Estes | ChC: Jason Marquis | Wrigley Field
Chicago, Illinois |
| 8:10 p.m. | Tigers | Royals | Det: Justin Verlander | KC: Zack Greinke | Ewing M. Kauffman Stadium
Kansas City, Missouri |
| 8:10 p.m. | Blue Jays | Twins | Tor: Jesse Litsch | Min: Kevin Slowey | Hubert H. Humphrey Metrodome
Minneapolis, Minnesota |
| 8:15 p.m. | Pirates | Cardinals | Pit: Paul Maholm | StL: Kyle Lohse | Busch Stadium
St. Louis, Missouri |
| 9:40 p.m. | Rockies | Diamondbacks | Col: Jeff Francis | Ari: Micah Owings | Chase Field
Phoenix, Arizona |
| 10:05 p.m. | White Sox | Angels | CWS: John Danks | LAA: Jered Weaver | Angel Stadium of Anaheim
Anaheim, California |
| 10:15 p.m. | Astros | Giants | Hou: Brandon Backe | SF: Matt Cain | AT&T Park
San Francisco, California |
| Miércoles, 14 de Mayo |
| Hora (Este) | Visitante | Local | Lanzador
Visitante | Lanzador
Local | Estadio |
| 2:05 p.m. | Mariners | Rangers | Sea: Carlos Silva | Tex: Scott Feldman | Rangers Ballpark in Arlington
Arlington, Texas |
| 3:05 p.m. | Red Sox | Orioles | Bos: Jon Lester | Bal: Daniel Cabrera | Oriole Park at Camden Yards
Baltimore, Maryland |
| 7:05 p.m. | Athletics | Indians | Oak: Joe Blanton | Cle: C.C. Sabathia | Progressive Field
Cleveland, Ohio |
| 7:05 p.m. | Braves | Phillies | Atl: Tom Glavine | Phi: Brett Myers | Citizens Bank Park
Philadelphia, Pennsylvania |
| 7:10 p.m. | Marlins | Reds | Fla: Ricky Nolasco | Cin: Bronson Arroyo | Great American Ball Park
Cincinnati, Ohio |
| 7:10 p.m. | Nationals | Mets | Was: Tim Redding | | Shea Stadium
Flushing, New York |
| 7:10 p.m. | Yankees | Rays | NYY: Kei Igawa | TB: James Shields | Tropicana Field
St. Petersburg, Florida |
| 8:05 p.m. | Dodgers | Brewers | LAD: Derek Lowe | Mil: Manny Parra | Miller Park
Milwaukee, Wisconsin |
| 8:05 p.m. | Padres | Cubs | SD: Jake Peavy | ChC: Ted Lilly | Wrigley Field
Chicago, Illinois |
| 8:10 p.m. | Tigers | Royals | Det: Kenny Rogers | KC: Luke Hochevar | Ewing M. Kauffman Stadium
Kansas City, Missouri |
| 8:10 p.m. | Blue Jays | Twins | Tor: Roy Halladay | Min: Boof Bonser | Hubert H. Humphrey Metrodome
Minneapolis, Minnesota |
| 8:15 p.m. | Pirates | Cardinals | Pit: Ian Snell | StL: Todd Wellemeyer | Busch Stadium
St. Louis, Missouri |
| 9:40 p.m. | Rockies | Diamondbacks | Col: Jorge De La Rosa | Ari: Brandon Webb | Chase Field
Phoenix, Arizona |
| 10:05 p.m. | White Sox | Angels | CWS: Jose Contreras | LAA: Jon Garland | Angel Stadium of Anaheim
Anaheim, California |
| 10:15 p.m. | Astros | Giants | Hou: Brian Moehler | SF: Patrick Misch | AT&T Park
San Francisco, California |
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