| Viernes, 16 de Mayo |
| Hora (Este) | Visitante | Local | Lanzador
Visitante | Lanzador
Local | Estadio |
| 2:20 p.m. | Pirates | Cubs | Pit: Tom Gorzelanny | ChC: Sean Gallagher | Wrigley Field
Chicago, Illinois |
| 7:05 p.m. | Nationals | Orioles | Was: Shawn Hill | Bal: Garrett Olson | Oriole Park at Camden Yards
Baltimore, Maryland |
| 7:05 p.m. | Brewers | Red Sox | Mil: Jeff Suppan | Bos: Daisuke Matsuzaka | Fenway Park
Boston, Massachusetts |
| 7:05 p.m. | Mets | Yankees | NYM: Johan Santana | NYY: Darrell Rasner | Yankee Stadium
Bronx, New York |
| 7:05 p.m. | Blue Jays | Phillies | Tor: David Purcey | Phi: Jamie Moyer | Citizens Bank Park
Philadelphia, Pennsylvania |
| 7:10 p.m. | Indians | Reds | Cle: Jeremy Sowers | Cin: Johnny Cueto | Great American Ball Park
Cincinnati, Ohio |
| 7:10 p.m. | Royals | Marlins | KC: Brett Tomko | Fla: Andrew Miller | Dolphin Stadium
Miami, Florida |
| 7:35 p.m. | Athletics | Braves | Oak: Dana Eveland | Atl: Jair Jurrjens | Turner Field
Atlanta, Georgia |
| 8:05 p.m. | Astros | Rangers | Hou: Shawn Chacon | Tex: Sidney Ponson | Rangers Ballpark in Arlington
Arlington, Texas |
| 8:15 p.m. | Rays | Cardinals | TB: Andy Sonnanstine | StL: Braden Looper | Busch Stadium
St. Louis, Missouri |
| 9:05 p.m. | Twins | Rockies | Min: Nick Blackburn | Col: Ubaldo Jimenez | Coors Field
Denver, Colorado |
| 9:40 p.m. | Tigers | Diamondbacks | Det: Jeremy Bonderman | Ari: Dan Haren | Chase Field
Phoenix, Arizona |
| 10:05 p.m. | Dodgers | Angels | LAD: Hiroki Kuroda | LAA: Joe Saunders | Angel Stadium of Anaheim
Anaheim, California |
| 10:10 p.m. | Padres | Mariners | SD: Chris Young | Sea: Miguel Batista | Safeco Field
Seattle, Washington |
| 10:15 p.m. | White Sox | Giants | CWS: Gavin Floyd | SF: Jonathan Sanchez | AT&T Park
San Francisco, California |
| Sábado, 17 de Mayo |
| Hora (Este) | Visitante | Local | Lanzador
Visitante | Lanzador
Local | Estadio |
| 1:05 p.m. | Mets | Yankees | NYM: Oliver Perez | NYY: Andy Pettitte | Yankee Stadium
Bronx, New York |
| 1:05 p.m. | Pirates | Cubs | Pit: Zach Duke | ChC: Carlos Zambrano | Wrigley Field
Chicago, Illinois |
| 1:10 p.m. | Rays | Cardinals | TB: Matt Garza | StL: Adam Wainwright | Busch Stadium
St. Louis, Missouri |
| 3:55 p.m. | Brewers | Red Sox | Mil: Dave Bush | Bos: Tim Wakefield | Fenway Park
Boston, Massachusetts |
| 3:55 p.m. | Dodgers | Angels | LAD: Chan Ho Park | LAA: Ervin Santana | Angel Stadium of Anaheim
Anaheim, California |
| 3:55 p.m. | Indians | Reds | Cle: Fausto Carmona | Cin: Aaron Harang | Great American Ball Park
Cincinnati, Ohio |
| 7:05 p.m. | Nationals | Orioles | Was: Odalis Perez | Bal: Brian Burres | Oriole Park at Camden Yards
Baltimore, Maryland |
| 7:05 p.m. | Astros | Rangers | Hou: Roy Oswalt | Tex: Vicente Padilla | Rangers Ballpark in Arlington
Arlington, Texas |
| 7:05 p.m. | Blue Jays | Phillies | Tor: A.J. Burnett | Phi: Adam Eaton | Citizens Bank Park
Philadelphia, Pennsylvania |
| 7:10 p.m. | Athletics | Braves | Oak: Rich Harden | Atl: Tim Hudson | Turner Field
Atlanta, Georgia |
| 7:10 p.m. | Royals | Marlins | KC: Brian Bannister | Fla: Scott Olsen | Dolphin Stadium
Miami, Florida |
| 8:05 p.m. | Twins | Rockies | Min: Livan Hernandez | Col: Greg Reynolds | Coors Field
Denver, Colorado |
| 8:10 p.m. | Tigers | Diamondbacks | Det: Armando Galarraga | Ari: Max Scherzer | Chase Field
Phoenix, Arizona |
| 9:05 p.m. | White Sox | Giants | CWS: Mark Buehrle | SF: Barry Zito | AT&T Park
San Francisco, California |
| 10:10 p.m. | Padres | Mariners | SD: Randy Wolf | Sea: Erik Bedard | Safeco Field
Seattle, Washington |
| Domingo, 18 de Mayo |
| Hora (Este) | Visitante | Local | Lanzador
Visitante | Lanzador
Local | Estadio |
| 1:10 p.m. | Royals | Marlins | KC: Zack Greinke | Fla: Burke Badenhop | Dolphin Stadium
Miami, Florida |
| 1:15 p.m. | Indians | Reds | Cle: Cliff Lee | Cin: Edinson Volquez | Great American Ball Park
Cincinnati, Ohio |
| 1:35 p.m. | Nationals | Orioles | Was: John Lannan | Bal: Jeremy Guthrie | Oriole Park at Camden Yards
Baltimore, Maryland |
| 1:35 p.m. | Brewers | Red Sox | Mil: Carlos Villanueva | Bos: Josh Beckett | Fenway Park
Boston, Massachusetts |
| 1:35 p.m. | Athletics | Braves | Oak: Justin Duchscherer | Atl: Jo-Jo Reyes | Turner Field
Atlanta, Georgia |
| 1:35 p.m. | Blue Jays | Phillies | Tor: Shaun Marcum | Phi: Kyle Kendrick | Citizens Bank Park
Philadelphia, Pennsylvania |
| 2:15 p.m. | Rays | Cardinals | TB: Edwin Jackson | StL: Kyle Lohse | Busch Stadium
St. Louis, Missouri |
| 2:20 p.m. | Pirates | Cubs | Pit: Phil Dumatrait | ChC: Jason Marquis | Wrigley Field
Chicago, Illinois |
| 3:05 p.m. | Astros | Rangers | Hou: Brandon Backe | Tex: Kason Gabbard | Rangers Ballpark in Arlington
Arlington, Texas |
| 3:05 p.m. | Twins | Rockies | Min: Kevin Slowey | Col: Jeff Francis | Coors Field
Denver, Colorado |
| 3:35 p.m. | Dodgers | Angels | LAD: Brad Penny | LAA: Jered Weaver | Angel Stadium of Anaheim
Anaheim, California |
| 4:05 p.m. | White Sox | Giants | CWS: John Danks | SF: Matt Cain | AT&T Park
San Francisco, California |
| 4:10 p.m. | Padres | Mariners | SD: Shawn Estes | Sea: Felix Hernandez | Safeco Field
Seattle, Washington |
| 4:10 p.m. | Tigers | Diamondbacks | Det: Nate Robertson | Ari: Randy Johnson | Chase Field
Phoenix, Arizona |
| 8:05 p.m. | Mets | Yankees | NYM: John Maine | NYY: Chien-Ming Wang | Yankee Stadium
Bronx, New York |
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