Carlos Torres has been very hittable as a starter for New York while Miami's Jacob Turner is winless in his last 10.
Those are the pitching matchups for Saturday's doubleheader at Citi Field as the NL East's worst teams continue a four-game set.
The most recognizable starter will be Matsuzaka (0-3, 8.00 ERA), who is now 0-7 with a 10.96 ERA in nine outings since his last victory Aug 27, 2012, for Boston.
The right-hander, who turned 33 on Friday, had his best effort in that span Sunday in Cleveland when he gave up one run over 5 2-3 innings in a 2-1 victory.
"He pitched an outstanding game," manager Terry Collins said. "Boy, I was really happy for him."
Matsuzaka's lone outing against Miami (54-92) was with the Red Sox last season, as he yielded four runs over 5 1-3 innings and did not get a decision in a 6-5 win.
He has given up three homers over 18 innings in 2013 while Alvarez (3-4, 4.34) has surrendered one over 74 2-3.
Alvarez hasn't thrown many pitches of late, but it hasn't always been his fault. A rain delay forced him out after 28 on Aug. 28 against Washington and a hamstring injury limited him to 79 on Sept. 2 as he earned a 4-3 win over the Cubs by allowing three runs over six innings.
Monday's 63 pitches in a 5-2 defeat to Atlanta occurred because he yielded all five runs in the fourth inning - his last of the contest.
The right-hander gave up two runs in a season-high 7 1-3 innings July 31 to earn a 3-2 victory over the Mets (65-81) in his lone 2013 start in this series.
He'll be followed to the mound in the nightcap by Turner (3-6, 3.43), who is 0-5 with a 4.53 ERA since the All-Star break. Opponents are batting .354 off him in his last four starts, but he is 1-0 with a 2.03 ERA in two starts against New York this year.
Turner will be opposed by fellow right-hander Torres (3-4, 3.53), who is 2-3 with a 5.68 ERA in six starts this year with teams batting .302 off him. Torres has never started against Miami with three scoreless innings in two career appearances.
Duda, hitting .200 in the season series, hit a three-run homer after his previous 11 had been solo shots.
"He's a big, strong guy," Collins said. "Everybody expects him to hit homers. I just expect him to drive runs in. And I think that swing tonight might really start him here in the last couple of weeks."
Stanton went deep twice for his ninth career multihomer effort to improve to 6 for 34 (.176) in the season series.
"We've got a few weeks left so, keep it up,'' Stanton said. "`It really doesn't matter what I do to finish the season, I'll never get back how terrible I've been. But to turn it completely around is something I need to do, something I better do."
Miami has won 10 of 16 meetings.