The struggling Toronto Raptors are dealing with their own woes, and they'll be down to eight healthy players Wednesday night when these teams meet in Canada looking to snap five-game losing streaks.
Lopez hoped his sprained right foot was healed enough to play Tuesday against New York, but he was ruled out before the game and is not scheduled to make the trip to Toronto.
The Nets (11-9) have lost the last five of the six games Lopez has missed after blowing a 17-point lead in a 100-97 loss to the Knicks. Brooklyn shot 52.9 percent - its second-best mark of the season - but only 45.2 percent in the second half as New York took advantage.
The Nets have led by at least nine points in four games during their skid.
"This was a winnable game, but we just couldn't quite close it," coach Avery Johnson said.
Lopez, who hopes to return Friday against Detroit, scored 27 points while Williams finished with 19 and nine assists Nov. 3 in a 107-100 home victory over Toronto, which concluded a winless five-game road trip with a 92-74 loss to Portland on Monday.
Frustration for the Raptors (4-18), who set a season low for points while shooting a season-worst 35.1 percent, hit a new high when forward Amir Johnson was ejected in the third quarter while trying to wrestle the ball from referee David Jones following a Blazers free throw. After being tossed, he threw his mouthpiece at Jones and had to be escorted off the court by teammates.
The league suspended Johnson without pay for this game.
"I told him we can't have that on a night where we're short-handed and we're in a situation where we're scrambling," coach Dwane Casey said. "We just gotta have more discipline than that."
Toronto already was playing without Andrea Bargnani and Kyle Lowry, who scored 28 points in last month's meeting with Brooklyn, after each left with injuries.
Bargnani played less than eight minutes and left after landing awkwardly following a dunk for his only two points of the game. X-rays on his elbow were negative, but he's not expected to play Wednesday.
Lowry also is likely to miss this game after not playing in the second half Monday due to a shoulder injury.
"Somebody grabbed his arm and he hit the floor and he just felt he had a knot in his back," Casey said.
The absences of Johnson, Bargnani and Lowry, along with Linas Kleiza, Alan Anderson and Landry Fields already being sidelined by injuries, leaves Casey with just eight healthy bodies. Toronto already has the most losses in the NBA and is shooting 38.9 percent over the last four games.
The Raptors have won five of the last six meetings in Canada, though MarShon Brooks was the only current Net who played in Toronto's 98-67 victory in the most recent meeting there April 26.
Ed Davis, who had a season-high 14 points against Portland on Monday, scored a career-high 24 in that contest.