Associated Press

Chambers could play significantly because Bobby Wade, who started the last two games and is second on the team with 20 receptions, is inactive, and the team released Bobby Engram to make room for running back Kolby Smith.

The other notable inactive for Kansas City is safety Jon McGraw, who was doubtful with a thigh injury. DaJuan Morgan will start in his place.

For Jacksonville, cornerback Rashean Mathis is returning to the starting lineup after missing a game with a broken index finger on his left hand. Mathis' return will move Reggie Nelson back to safety. Nelson struggled last week at Tennessee in Mathis' spot.